In the News Research

Taylor Institute develops mice available from JAX Labs.

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Also Known As: δ* KI

δ* KI is a CRISPR/cas9-made knock-in allele with a T269Y mutation in Gabrd exon 8 that renders δ-containing receptor populations insensitive to picrotoxin (PTX). These mice allow chemogenetic isolation of δ-containing GABAA receptors, and may be useful for neurological studies of receptor, ion channel and synapse biology, neurotransmitters, and glutamate/GABA transmission.

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