Researchers in St. Louis have launched a study into whether a long-used antidepressant can reduce the likelihood that COVID-19 will turn deadly.
Category: Research
Wash U to test OCD drug for potential COVID-19 treatment
Researchers at Washington University School of Medicine are recruiting COVID-19 patients for a clinical trial that will examine whether an existing anti-depressant can be an effective treatment for COVID-19.
WUSM to break ground on major neuroscience research hub (Links to an external site)
Washington University in St. Louis will begin construction in March on what will be one of the largest neuroscience research buildings in the country.
New antidepressants on horizon (Links to an external site)
Neuroactive steroid drugs result from Taylor Family Institute, pharma collaboration
Creative workshops help kids relieve stress with art (Links to an external site)
Glowinski, artist Outlaw address mental health through artwork.
$10 million gift aimed at improving treatments for mental illness (Links to an external site)
Philanthropists Andrew and Barbara Taylor and the Crawford Taylor Foundation have committed $10 million to Washington University School of Medicine in St. Louis to continue research to investigate the scientific underpinnings of psychiatric illnesses, with the goal of improving diagnosis and treatment.
How team sports change a child’s brain (Links to an external site)
Adult depression has long been associated with shrinkage of the hippocampus, a brain region that plays an important role in memory and response to stress. Now, new research from Washington University in St. Louis has linked participation in team sports to larger hippocampal volumes in children and less depression in boys ages 9 to 11.
Engineering treatments for the opioid epidemic (Links to an external site)
A biomedical engineer at Washington University in St. Louis is developing a therapeutic option that would prevent the opiates from crossing the blood-brain barrier, preventing the high abusers seek.
Blunting pain’s emotional component (Links to an external site)
Blocking a type of opioid receptor restores motivation
Young kids with suicidal thoughts understand concept of death (Links to an external site)
Study refutes idea that children who talk about suicide don’t understand it
The view from the chair (Links to an external site)
Seven years ago, Chancellor Mark S. Wrighton (left) asked Andrew C. Taylor, executive chairman of Enterprise Holdings and a life trustee of the university, to chair the public phase of Leading Together.
Taylor Institute develops mice available from JAX Labs. (Links to an external site)
Also Known As: δ* KI δ* KI is a CRISPR/cas9-made knock-in allele with a T269Y mutation in Gabrd exon 8 that renders δ-containing receptor populations insensitive to picrotoxin (PTX). These mice allow chemogenetic isolation of δ-containing GABAA receptors, and may be useful for neurological studies of receptor, ion channel and synapse biology, neurotransmitters, and glutamate/GABA transmission.
MRI scans shows promise in predicting dementia (Links to an external site)
Brain changes evident in scans before memory, cognitive decline
Taylors Provide $10 Million to Accelerate Psychiatric Drug Development (Links to an external site)
In 2012, Andrew and Barbara Taylor and the Crawford Taylor Foundation pledged $20 million to the Department of Psychiatry at Washington University’s School of Medicine to establish a research institute dedicated to advancing new treatments for mental illnesses. Just six years later, investigators in the department’s Taylor Family Institute for Innovative Psychiatric Research are on […]
Depression in Young Children is Treatable (Links to an external site)
Parent-child interactive therapy decreases depressive symptoms in kids.
Depressed patients see quality of life improve with nerve stimulation (Links to an external site)
A national study led by institute affiliate Charles Conway, MD, indicates that people treated with nerve stimulation experience significant improvements in quality of life, even when their depression symptoms don’t completely dissipate.
New approach to developing antidepressants (Links to an external site)
In the new research, Steve Mennerick, Institute scientific director, and his colleagues focused on GABA receptors located on neurons in the brain’s hippocampus, a part of the brain involved in learning and memory. Using CRISPR, they mutated the delta-type GABA receptors to isolate and test their role in brain functioning.
Laughing gas studied as depression treatment (Links to an external site)
Nitrous oxide, or laughing gas, has shown early promise as a potential treatment for severe depression in patients whose symptoms don’t respond to standard therapies. The pilot study was believed to be the first research in which patients with depression were given laughing gas.